Research Fertility

Study: 2450 MHz radiation linked to oxidative stress and apoptosis signals in cultured ovarian cells

October 24, 2026 (EMFS)

Oct 8, 2026 (original)

Source: Cells

Source category: Research

A study in the journal Cells, published 8 October 2026, exposed cultured SKOV3 human ovarian epithelial cells to 2450 MHz radiofrequency radiation, the band used by Wi-Fi and microwave ovens, for 30, 60 or 120 minutes at a measured 13.44 volts per metre. Viability was unchanged at 24 hours but fell in the 120-minute group at 48 hours, while reactive oxygen species and nitrite rose and ATP levels shifted over time. The cells also showed apoptosis-related gene and staining changes that grew with exposure time. The authors note that ovarian-cell models in general remain little studied.

Exposure note: The methods of the paper state that temperature was monitored during exposure and remained comparable between the sham-control and exposed groups, which the authors treat as confirming non-thermal conditions. No specific absorption rate (SAR) is reported.

Quotes

"RFR exposure did not significantly reduce MTT-based viability/metabolic activity at 24 h post-exposure; at 48 h, a significant reduction was observed in the 120-min group compared with the control and 30-min groups."

— Ahmad et al.

"Exposed cells showed progressive ROS accumulation, increased nitrite levels, and changes in ATP levels, with an increase at 30 min followed by lower levels at 60 and 120 min relative to 30 min, while the JC-1 red/green ratio showed no significant change."

— Ahmad et al.

"Overall, these findings indicate an exposure-associated cellular stress phenotype involving redox, ATP status, and apoptosis-related alterations in SKOV3 cells under defined in vitro conditions."

— Ahmad et al.

Exposure

"Cells were exposed for 30, 60, and 120 min under controlled conditions at a measured electric field intensity of 13.44 V/m."

— Ahmad et al., Cells (2026), Abstract

"Temperature was monitored during exposure and remained comparable between the sham-control and RFR-exposed groups, confirming non-thermal exposure conditions."

— Ahmad et al., Cells (2026), Methods

"A sample-specific SAR value was not determined for the present horn-antenna in vitro configuration; therefore, no extrapolated SAR value is reported, and the exposure was characterized using the directly measured E-field, spatial variation, exposure geometry, and thermal stability."

— Ahmad et al., Cells (2026), Methods

Location

📍 India

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Source

Radiofrequency Radiation Alters Redox Homeostasis, ATP Status, and Apoptosis-Associated Responses in Human Ovarian Epithelial Cells pubmed.ncbi.nlm.nih.gov

📄 Underlying Research

Radiofrequency Radiation Alters Redox Homeostasis, ATP Status, and Apoptosis-Associated Responses in Human Ovarian Epithelial Cells

Ahmad S, Nagar G, Yadav N, Singh S, Shrivastava A, Singh R (2026) Cells Journal Level 0ⓘ

🔗 DOI 📚 PubMed 📰 Full Article

Study: 2450 MHz radiation linked to oxidative stress and apoptosis signals in cultured ovarian cells

Source

📄 Underlying Research

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