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🔬 Study: 2.45 GHz Radiofrequency Reprograms Immune Cell Survival Pathways at Subthermal Levels

May 20, 2026 (EMFS)
Apr 24, 2026 (original)
Source: International Journal of Molecular Sciences
Source category: Research
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A study finds that in vitro exposure of RAW 264.7 macrophages (immune cells) to 2.45 GHz radiofrequency fields — alongside lipopolysaccharide (LPS) and/or the SARS-CoV-2 spike protein (CSP) — reprogrammed interactions between mitochondria, lysosomes (cellular recycling compartments), and cell death pathways at subthermal exposure levels.

"The combination of RF-EMF and infectious agents reprogrammed the interaction between mitochondria/lysosomes/nitric oxide (NO)/cell death in macrophages in a time- and stimulus-dependent manner."

— Sueiro-Benavides RA et al. (study authors)

"Selective loss of viability in cells exposed to RF and LPS [lipopolysaccharide] was observed at 6 h, consistent with early defects in membrane permeability."

— Sueiro-Benavides RA et al. (study authors)

Exposure

"The cells were then irradiated for 6, 24 or 48 h in a GTEM chamber [...] at the point of maximum field uniformity."

— Sueiro-Benavides RA et al. (study authors)

Exposure parameters: 2450 MHz, 12 W transmitted power, 102.8 V/m measured field, 28 W/m² incident power density, and mean SAR 0.1740 W/kg for the 24-well plate (Table 3).

Glossary

RAW 264.7: A standard mouse macrophage-like cell line used in laboratory immune and inflammation studies.

24-well plate: A plastic cell-culture plate with 24 separate wells for growing cells under different experimental conditions.

Lipopolysaccharide (LPS): A bacterial cell-wall component commonly used in lab studies to trigger inflammatory immune responses.

Source

Radiofrequency Fields at 2.45 GHz Reprogram Mitochondria-Lysosome Crosstalk and Modulate the Survival/Death of Macrophages Exposed to LPS and/or the SARS-CoV-2 Spike Protein pubmed.ncbi.nlm.nih.gov

📄 Underlying Research

Radiofrequency Fields at 2.45 GHz Reprogram Mitochondria-Lysosome Crosstalk and Modulate the Survival/Death of Macrophages Exposed to LPS and/or the SARS-CoV-2 Spike Protein

Sueiro-Benavides RA et al. (2026) International Journal of Molecular Sciences Journal Level 0

🔗 DOI 📚 PubMed

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