"RF-EMF and PMF treatments significantly alleviated these alterations by reducing tissue injury, apoptosis, inflammation, and oxidative stress while restoring myelin integrity."
"The combined RF-EMF + PMF therapy produced the most robust protective effects across all evaluated parameters."
"Electromagnetic field-based therapies may offer a promising approach for treating neuroinflammation-associated disorders."
Exposure parameters
"For the generation of 1 Hz, 0.5 mT of PMF, 2 coils with 400 turns and a winding diameter of 6.5 cm were used. [...] These coils were fixed crosswise under each animal cage, and these inductive applicators were placed crosswise on the diagonal in such a way that they create a 0.5 mT magnetic field on the animal cage floor."
"The 27.12 MHz RF applicator was essentially an RF antenna. However, since our aim was to obtain sufficiently homogeneous electric fields in cages, these antenna applicators have PCB RF antennas. 15×15 cm frame PCB antennas were used as 2 pieces on each cage. The aim was to create an average RF field of 10 V/m in the living environment of animals roaming freely in the cage. It can be said that sufficiently homogeneous electric fields were obtained when the field change is less than 10% in the measurements taken at many points in the living space of the cage."
Radiofrequency and pulsed magnetic fields attenuate LPS-induced neuroinflammation and demyelination via PI3K/AKT/HIF-1α-mediated neurovascular protection
Bindal et al. (2026) Molecular Biology Reports Journal Level 1ⓘ
