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Rat study links 50 Hz magnetic field exposure during brain development to inflammation markers and reduced synaptic proteins

September 29, 2026 (EMFS)
Aug 21, 2026 (original)
Source: Indian Journal of Experimental Biology
Source category: Research
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Öztürk and colleagues at three Turkish university biophysics departments (Karadeniz Technical, Aydın Adnan Menderes and Istanbul University-Cerrahpasa) exposed Sprague-Dawley rats to a 50 Hz, 500 microtesla magnetic field during the prenatal period, the postnatal period, or both, then measured inflammatory markers and synaptic proteins in the cortex and hippocampus by ELISA. Combined exposure raised the inflammatory markers IL-17A and IFN-γ and reduced the synaptic proteins PSD-95 and Syn1, while IL-4 was unchanged. The authors suggest such fields may trigger inflammation in young rat brains and impair synaptic transmission, and call for further research. The study appears in the Indian Journal of Experimental Biology.

"Combined prenatal and postnatal exposure to ELF-MF significantly increased IL-17A levels in the hippocampus and cortex and elevated IFN-γ levels in the cortex."

— Öztürk et al., Indian Journal of Experimental Biology

"Additionally, in the combined prenatal and postnatal exposure group, ELF-MF significantly reduced PSD-95 levels in both the cortex and hippocampus, and Syn1 levels in the hippocampus."

— Öztürk et al., Indian Journal of Experimental Biology

"However, there was no change in IL-4 levels."

— Öztürk et al., Indian Journal of Experimental Biology

"Our results suggest that ELF-MF may trigger inflammation in the brains of young rats, potentially impairing synaptic transmission, particularly in the hippocampus where reduced Syn1 may limit presynaptic neurotransmitter release."

— Öztürk et al., Indian Journal of Experimental Biology

Exposure

"The rats were exposed to 50 Hz, 500 µT ELF-MF during prenatal, postnatal, or both periods."

— Öztürk et al., Indian Journal of Experimental Biology

Location

📍 Istanbul, Turkey

Map: Istanbul, Turkey

Source

Impact of extremely low-frequency magnetic fields on neuroinflammation and synaptic protein development in prenatal and postnatal rat brains or.niscpr.res.in

📄 Underlying Research

Impact of extremely low-frequency magnetic fields on neuroinflammation and synaptic protein development in prenatal and postnatal rat brains

Öztürk H, Kılıç MA, Ercan AM, Saribal D (2026) Indian Journal of Experimental Biology Journal Level 0ⓘ

🔗 DOI

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