DRAFT: Pulsed electromagnetic fields protected skin collagen from UV damage in laboratory study — EMF Signal

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International Journal of Molecular Sciences

Therapeutic

Pulsed electromagnetic fields protected skin collagen from UV damage in laboratory study

September 18, 2026 (EMFS)

Sep 4, 2026 (original)

Source: International Journal of Molecular Sciences

Source category: Therapeutic

Byun and colleagues at Gachon University and collaborating clinics and companies in South Korea report in the International Journal of Molecular Sciences that pulsed electromagnetic field (PEMF) exposure reduced ultraviolet B-induced collagen loss in skin fibroblast cultures and an in vivo model. The study used the commercial PEMF device Corefacial and links the protective effect to A2A adenosine receptor signaling and reduced NLRP3 inflammasome activation. The authors stress that the findings do not prove the proposed mechanism and should be read as evidence from a UVB-specific experimental model rather than a comprehensive model of solar photoaging.

🔬 This research is covered in EMF Signal's section on therapeutic EMF applications. It investigates controlled use of electromagnetic fields as potential treatment, not environmental exposure.

Note: The journal's conflict-of-interest disclosure states that two authors are employed by LIBON Inc., which funded the research through grants, and two other authors direct dermatology clinics. According to the disclosure, the funder had no role in study design, analyses, interpretation or the decision to publish.

"Pulsed electromagnetic field (PEMF) stimulation is a non-optical biophysical modality that may modulate inflammatory and matrix responses."

— Byun et al., International Journal of Molecular Sciences

"In UVB-exposed fibroblasts, PEMF restored A2AAR and PKA protein levels, cAMP levels, and the pNLRP3/NLRP3 ratio, similar to the effects of the A2AAR agonist CGS-21680."

— Byun et al., International Journal of Molecular Sciences

"In the in vivo UVB model, PEMF similarly increased A2AAR and PKA protein levels, cAMP levels, and the pNLRP3/NLRP3 ratio, while attenuating IL-1β/NF-κB/MMP-associated responses and preserving dermal collagen."

— Byun et al., International Journal of Molecular Sciences

"These findings are consistent with, but do not prove, involvement of A2AAR/cAMP/PKA-related signaling and inhibitory NLRP3 phosphorylation in the PEMF response."

— Byun et al., International Journal of Molecular Sciences

"These results should be interpreted as evidence from a UVB-specific experimental model rather than a comprehensive model of solar photoaging."

— Byun et al., International Journal of Molecular Sciences

Location

📍 South Korea

Map: South Korea

Source

Pulsed Electromagnetic Field Exposure Attenuates Ultraviolet B-Induced Dermal Collagen Loss in Association with A2A Adenosine Receptor Signaling emf-portal.org

📄 Underlying Research

Pulsed Electromagnetic Field Exposure Attenuates Ultraviolet B-Induced Dermal Collagen Loss in Association with A2A Adenosine Receptor Signaling

Byun KA, Lee JI, Oh S, Kim SE, Seo SB, Son KH, Byun K (2026) International Journal of Molecular Sciences Journal Level 0ⓘ

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🇰🇷 Korean lab study: PEMF exposure reduced UVB-induced skin collagen loss via adenosine receptor signaling. A UVB-specific model, the authors note.

Source: International Journal of Molecular Sciences

🧭 Front page section (YAML field: `categories`)

Therapeutic EMF Applications
categories: therapeutic

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