A Journal of Applied Clinical Medical Physics dosimetry study measured how Tumor Treating Fields (TTFields) transducer arrays affect megavoltage photon irradiation when TTFields are combined with radiotherapy.
The authors report dose reductions of about 2-4% at depth and a substantial increase in surface dose, while repositioning the array reduced but did not eliminate surface-dose hotspots. This belongs in EMF Signal's therapeutic EMF section because it concerns controlled clinical TTFields use, not environmental exposure.
"The presence of the TTFields array resulted in statistically significant attenuation at depth, with dose reductions of approximately 2%-4% up to 10 cm (p < 0.001)."
"Surface dose increased substantially, with MOSFET and diode measurements demonstrating enhancement factors ranging from 1.81 to 1.87 relative to baseline."
"Repositioning the array reduced peak surface dose by up to 40%."
"TTFields transducer arrays introduce clinically meaningful dosimetric perturbations, characterized by significant surface dose enhancement, and measurable attenuation at depth."
Dosimetric impact of radiofrequency tumor treating field arrays on dose on surface and at depth.
Sarah Ashmeg et al. (2026) Journal of Applied Clinical Medical Physics Journal Level 1ⓘ
Archived copy for date/quote verification
🧠 TTFields arrays measurably alter photon dose during radiotherapy, dosimetry study reports Dose at depth fell about 2-4%; surface dose rose substantially. Repositioning reduced hotspots. Source: J Appl Clin Med Phys
categories)therapeutic